Wide spread of skin diseases dictates a necessity in early and maximum accurate diagnostics, because severe forms of skin diseases decrease greatly quality of life of a patient and his family, promote development of a psychosomatic disorders. Visual evaluation of symptoms and severity of a disease often has subjective nature.
Total thickness of skin without subcutaneous fat varies from bits of a millimeter to 4 mm.
Exiting systems for NLS-diagnostics (bioplasm nls health analyzer) are equipped with high-frequency linear generators (1.4 GHz) allowing to visualize the most superficial structures, in particular skin. However to evaluate condition of ultrafine structures of skin such frequency is not enough sometimes. That is why dermatologists started to use special devices with sensors of 40 GHz operating frequency, which allow to see the finest structures of skin layers down to the level of large carbohydrate molecules and peptides.
But at the same time due to significant cost of such equipment if becomes unaffordable for wide application in the majority of clinics. Taking into account a need in evaluation of regional lymph nodes and tumors of soft tissues, apparently the optimal decision is to use devices for non-linear diagnostics equipped with non-linear sensors.
Bioplasm NLS health analyzer has axial resolution of 30 µm. Application of this device allows to study epidermis on cellular and sub-cellular levels. Nowadays objectives and limits of three-dimensional NLS-ultramicroscanning research in dermatology have become very broad.
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